multiple sclerosis

Multiple sclerosis affects the brain and spinal cord. Early symptoms of multiple sclerosis include weakness, tingling, numbness,
and blurred vision. Other possible warning signs are muscle stiffness, thinking problems, and urinary problems. A multiple sclerosis diagnosis is made by the history of symptoms and a neurological exam, often with the help of tests such as an MRI or a spinal tap. No one’s sure what causes multiple sclerosis, but it may be hereditary. There are currently no cures for multiple sclerosis, but treatment can relieve worsening of symptoms.

Adeona is developing Trimesta (estriol), an investigational oral drug, for the treatment of relapsing-remitting multiple sclerosis. Estriol is a hormone produced during pregnancy that has been scientifically documented to reduce symptoms in women suffering from with certain autoimmune diseases, including multiple sclerosis. More than 2.5 million people worldwide (approximately 400,000 in the United States) are afflicted with multiple sclerosis, with two to three times as many women affected as men. A randomized, double-blind, placebo-controlled clinical trial is currently underway at 15 centers in the United States.